Adenosine

(Adenocard)

 

INDICATIONS:

 

  • PSVT, SVT

 

ADMINISTRATION:

 

  • Rapid IV, IO

 

DOSAGE:

 

ADULT:

 

  • Initial dose up to 12 mg rapid IV bolus
  • 12 mg within 1-2 minutes of continuing SVT – given rapid IV bolus
  • 12 mg dosage may be repeated once in 5 minutes to maximum dose of 36 mg

 

PEDIATRIC:

 

  • 0.1 mg/kg (over 1 to 2 sec) IV followed by rapid saline flush. Max initial dose 6 mg.
  • 0.2 mg/kg within 1-2 minutes of continuing SVT – given rapid IV bolus. Max single dose 12 mg.

 

THERAPEUTIC EFFECTS:

 

  • Slows conduction time through the A-V node
  • Interruption of reentry pathways through the A-V node
  • Restoration of NSR in patients with PSVT

 

RELATIVE CONTRAINDICATIONS:

 

  • Second or third degree A-V block

 

SIDE EFFECTS:

 

  • Short-lasting first, second or third degree AV block
  • Transient Asystole
  • Various arrhythmias lasting only a few seconds

 

SPECIAL NOTES / RESTRICTIONS:

 

  • The onset of the effect is generally within less than one minute
  • Reported adverse experiences are predictable, short lived and easily
  • tolerated