Dopamine

(Intropin)

 

 

Indications:

 

  • Cardiogenic shock associated with hypotension
  • Contraindications:
  • Hypovolemic shock where complete fluid resuscitation has not occurred
  • Uncorrected tachydysrhythmias or V-Fib.
  • Side Effects:
    • Tachydysrhythmias
    • Ectopy
    • Headache
    • Angina
    • Nausea
    • Vomiting

 

ADMINISTRATION:

 

  • IV infusion, IO

 

Adult Dosage:

 

  • 5-20 mcg/kg/min IV/IO
  • Mix 80 mg (2 mL) Dopamine in 50 mL NS bag = 1600 mcg concentration use 60 gtt set for desired rate.
  • 2-5 mcg/kg/min initially, up to 20 mcg/kg/min titrated to B/P

 

PEDIATRIC:

 

  • 2-5 mcg/kg/min initially, up to 20 mcg/kg/min titrated to B/P

 

THERAPEUTIC EFFECTS:

 

  • Increases perfusion & BP by increasing cardiac output & systemic arterial pressure while dilating vessels to the heart, brain & kidneys
  • Depending on dose; stimulates alpha, beta, & dopamine receptor sites

 

RELATIVE CONTRAINDICATIONS:

 

  • Hypovolemic shock where complete fluid resuscitation has not occurred.
  • Uncorrected tachydysrhythmias or VF

 

SIDE EFFECTS:

 

  • Tachydysrhythmias
  • Ectopy
  • Headache
  • Angina
  • Nausea/Vomiting

 

SPECIAL NOTES / RESTRICTIONS:

 

  • Titrate according to blood pressure
  • Range is 2-20 mcg/kg/min