- Skeletal muscle relaxation during operative and manipulative procedures
- Facilitate management of patients undergoing mechanical ventilation
- Adjunct to general anesthesia
- 1.5mg/kg over 30 seconds; not to exceed 150mg total dose
- Prevents neuromuscular transmission by blocking the effect of acetylcholine at the myoneural junction
- Hypersensitivity to succinylcholine
- History of malignant hyperthermia
- Skeletal muscle myopathies
- Penetrating eye injury
- Cardiac arrhythmias
- Increased intraocular pressure
- Muscle fasciculations
REVISED FORMULARY 2010 Page 78
SPECIAL NOTES / RESTRICTIONS:
- Succinylcholine has no effect on consciousness, pain threshold, or cerebration. Must be used only with adequate sedation.
- In elderly time of onset may be delayed due to slower circulation time in cardiovascular disease.
- Use with extreme caution in patients with severe burns, electrolyte imbalance, hyperkalemia, and those receiving quinidine or digitalis.
- The potential for releasing histamine is present following succinylcholine use. Serious histamine-mediated flushing, hypotension, and bronchoconstriction are, however, uncommon in clinical usage.
- Incidence of side effects increase with second or subsequent doses.
- STORAGE: Refrigerate at 35 O - 46 O F. Multi-dose vials are stable for up to 14 days at room temperature.
- RSI MAY BE initiated by Standing Order or Protocol. It is RECOMMENDED – where feasible – that On-Line Medical Control be obtained prior to initiation– but this should not supercede the appropriate care of the patient.
- 100% QI / PI is required for ALL RSI runs.