Indications:

 

• Anticholinergic drug used in bradycardias
• Organophosphate poisoning

• Pediatric:
  • Symptomatic bradycardia secondary to AV block or vagal activity 2nd line after Epinephrine for bradycardia due to poor perfusion or hypotension.

 

Contraindications:

 

• Tachycardia
• Hypertension (rule out head injury first)

 

Side Effects:

 

• tachycardia
• dry mouth
• thirst
• flushing of skin
• blurred vision
• headache
• pupillary dilation
• urine retention

 

Adult Dosage:

 

• Bradycardia

 

1. • 1 mg IV administration; repeat Q 3-5 minutes to a total dose of 3 mg

 

• Organophosphate Poisoning:

 

• • To block parasympathetic response:

 

• • • 1 - 2 mg; IV dose repeated Q 5 minutes until a decrease in secretions are observed or to total dose of 6 mg.

 

Pediatric:

 

• Bradycardia

 

• • 0.02 mg/kg (0.2 ml/kg) IV, Minimum 0.1 mg,
  • Maximum single dose 0.5 mg child; 1 mg adolescent.
  • May be repeated once

 

• Organophosphate Poisoning:

 

• • To block parasympathetic response:

 

• • • Children: 0.05 to 0.1 mg/kg Loading dose. Adolescents: 2 mg
    • Repeat every 10 – 15 minutes until rales and bronchial secretions resolved.