Protocol Status: PUBLISHED
Protocol:
Version: 2026.01
Effective Date:
Last Reviewed:
Medical Director Approval:
Clinical Note: This content reflects current GCEMS clinical guidelines as of the dates listed above. If content appears inconsistent with current policy, use the most recent approved guideline and notify leadership for correction.

Nausea - Vomiting

 

History:

 

  • Age
  • Time of last meal
  • Last bowel movement/emesis
  • Improvement or worsening with food or activity
  • Duration of problem
  • Other sick contacts

 

Significant Findings:

 

  • Pain
  • Character of pain
  • Constant
  • Intermittent
  • Sharp
  • dull
  • Distention
  • Constipation
  • Diarrhea
  • Anorexia
  • Radiation

 

Associated symptoms (helpful to localize source)

 

  • Fever
  • Headache
  • Blurred Vision
  • Weakness
  • Malaise
  • Mental status changes
  • Myalgia
  • Cough
  • Dysuria
  • Rash

 

Differential:

 

  • CNS
    • Increased pressure
    • Headache
    • Stroke
    • CNS lesions
    • Trauma/hemorrhage
    • Vestibular
  • Myocardial infarction
  • Drugs
  • GI/Renal disorders
  • Diabetic Ketoacidosis
  • Gynecologic disease
    • Ovarian cyst
    • PID
  • Infections
  • Electrolyte abnormalities
  • Pregnancy
  • Psychological

 

Treatment:

 

  • Oxygen
  • Obtain BGL
  • 12 Lead EKG
  • Initiate IV

 

Signs of hypotension ?

 

  • Yes

 

 

8-15 kg ?

 

  • Yes

 

    • Zofran 2 mg slow IV/IM over 2 min

 

≥ 15 kg

 

  • Yes

 

    • Zofran 4 mg slow IV/IM; may be repeated in 10 mins;  4 mg ODT can be substituted

 

  • Notify receiving facility or contact Medical Control

 

PEARLS:

 

  • ODT Zofran (Ondansetron) 4 mg can be given to a previously healthy child > 6 months of age.
  • Use Handtevy for pediatric drug dosages.
  • Zofran (Ondansetron) can cause QT widening.
  • Use ODT (orally disintegrating tablets) with caution in adult patients complaining of abdominal pain.
  • For ODT, place one tablet on top of patient's tongue.
  • Beware of vomiting in children. Pyloric stenosis, bowel obstruction, and central nervous system processes (bleeding tumors, or increased cerebral spinal fluid pressure) all often present with vomiting.
  • Document the mental status and vital signs prior to administration of antiemetic medications.