Protocol Status: PUBLISHED
Protocol:
Version: 2026.01
Effective Date:
Last Reviewed:
Medical Director Approval:
Clinical Note: This content reflects current GCEMS clinical guidelines as of the dates listed above. If content appears inconsistent with current policy, use the most recent approved guideline and notify leadership for correction.

Ceftriaxone

(Rocephin)

 

GCEMS Protocol:

 

  • Sepsis
  • Open Fractures

 

Indications:

 

  • SIRS criteria x 2 and known or suspected pulmonary source of infection

 

Contraindications:

 

  • Allergy to Ceftriaxone, penicillin or their derivative

 

Adult:

 

  • Sepsis

 

    • 2 G mixed in 50 mL or 100 mL of NS infused IV/IO over 10 minutes

 

  • Open Fractures

 

    • 2 G mixed in 50 mL of NS infused IV/IO over 10 minutes

 

Peds:

 

  • Open Fractures:

 

    • 50 mg/kg to a max dose of 1 g IV over 10 minutes