Protocol Status: PUBLISHED
Protocol:
Version: 2026.01
Effective Date:
Last Reviewed:
Medical Director Approval:
Clinical Note: This content reflects current GCEMS clinical guidelines as of the dates listed above. If content appears inconsistent with current policy, use the most recent approved guideline and notify leadership for correction.

Succinylcholine

(Anectine)

 

INDICATIONS:

 

  • Facilitate endotracheal intubation by paralysis
  • Facilitate management of patients undergoing mechanical ventilation

 

DOSAGE:

ADULT:

 

  • 1.5mg/kg over 30 seconds; not to exceed 150mg total dose

 

PEDIATRIC:

 

  • NOT INDICATED.

 

CONTRAINDICATIONS:

 

  • Hypersensitivity to succinylcholine
  • History of malignant hyperthermia
  • Skeletal muscle myopathies
  • Penetrating eye injury

 

SIDE EFFECTS:

 

  • Apnea
  • Cardiac arrhythmias
  • Increased intraocular pressure
  • Muscle fasciculations

 

SPECIAL NOTES / RESTRICTIONS

 

  • Succinylcholine has no effect on consciousness, pain threshold, or cerebration. Must be used only with adequate sedation.
  • In elderly time of onset may be delayed due to slower circulation time in cardiovascular disease.
  • Use with extreme caution in patients with severe burns, electrolyte imbalance, hyperkalemia, and those receiving Quinidine or Digitalis.